Raman spectroscopic imaging for investigations of de novo lipogenesis in hepatocellular carcinoma
T Tolstik, C Marquardt, C Matthäus, C Beleites, C Krafft, C Bielecki, O Dirsch, U Settmacher, J Popp, A Stallmach · Zeitschrift für Gastroenterologie · 2014 · Heft 08
Bibliografische Angaben
Zusammenfassung
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide with incidence rate of 692,000. The early diagnosis of HCC is a crucial step for effective treatment what may be a challenge for pathologist. New approaches are needed to be developed that are able to detect molecular changes at once and to use this "fingerprint" for an objective tumor differentiation. Raman spectroscopy has been recently recognized as a powerful technique for tissue and cell diagnostics because the method allows localizing characteristic vibration pattern in the label-free biological samples. In order to confirm the diagno…
