CareLit Fachartikel
Expression analysis of the macrophage-capping protein (CapG) in single circulating tumor cells (CTCs) isolated from blood samples of breast cancer patients
Y Decker, MHD Neumann, M Fleisch, H Neubauer, D Niederacher, T Fehm · Geburtshilfe und Frauenheilkunde · 2014 · Heft 09
Dokument
1144254
CareLit-ID
Jahr
2014
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Objective: Detection of CTCs by the CellSearch system is based on immunomagnetic enrichment of EpCAM+ cells. Supplementary tools are necessary to isolate and characterize also EpCAM negative CTCs. CapG was shown to be involved in cancer cell migration and invasiveness of breast cancer (BC). Aim of this work was to characterize CapG expression in CTCs of BC patients. Material and methods: CTCs were enriched and detected in blood samples using the CellSearch system. EpCAM+ cells were isolated from CellSearch cartridges by the CellCelector system (ALS, Jena, Germany), an automated scanning microscope and micromanip…
Schlagworte
Blood
Breast
Workflow
Germany
Work
After
Tumor
Geburtshilfe und Frauenheilkunde
