Sentinel detection in endometrial cancer: technique, experience and results for isthmocervical labelling and the use of SPECT/CT

Objective: We analyze the clinical feasibility of transcervical subepithelial injection into the isthmocervical region of the myometrium as new labeling technique for sentinel detection in endometrial carcinoma (EC). We compared sentinel lymph node (SLN) detection rate by single photon emission computed tomography with CT (SPECT/CT) with planar lymphoscintigraphy. Methods: In all patients transcervical injection of 10 MBq Technetium-99 m-nanocolloid was performed into the isthmocervical myometrium without anaesthesia in a unicentric prospective study. After 40 (30 – 60) minutes, lymphoscintigraphy and SPECT/CT w…