25-hydroxyvitamin D deficiency is associated with infections and mortality in cirrhosis
F Finkelmeier, B Kronenberger, S Zeuzem, A Piiper, O Waidmann · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Bibliografische Angaben
Zusammenfassung
Objective: Vitamin D is involved in many biological functions such as proliferation, apoptosis, cellular signaling and anti-inflammation. Recently, an increased incidence of 25(OH)D3 deficiency has been found in subjects suffering from chronic liver diseases and the extent of 25(OH)D3 deficiency in the patients correlated with the severity of liver dysfunction. We hypothesized that low vitamin D levels might be associated with inflammatory responses and infectious complications in cirrhotic patients. Therefore, we performed a prospective cohort study investigating the relation of 25(OH)D3 levels with stages of c…