Verification of the breast cancer progression-associated miRNA hsa-miR-199a-5 p using NanoString® platform
S Schultz, H Bartsch, K Petat-Dutter, M Bonin, H Seeger, S Kahlert, U Vogel, T Fehm, K Soltar, D Niederacher, H Neubauer · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
A fundamental and clinically important step during breast tumourigenesis is the transition from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). Improved knowledge of this transition from pre-invasive to invasive breast cancer will pave the way for novel preventative and therapeutic strategies. We have previously reported on differential expression of the miRNA hsa-miR-199a-5 p in 15 matched pairs of DCIS and IDC areas isolated by laser capture microdissection (LCM) from formalin fixed and paraffin embedded (FFPE) breast cancer tissues using Illumina miRNA BeadChip microarray platform. Differe…
