Decrease in liver fibrosis after achieving SVR in patients with chronic Hepatitis C infection
K Kozbial, S Beinhardt, C Freissmuth, A Stättermayer, R Stern, P Munda, M Trauner, P Ferenci, H Hofer · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and Aims: Liver fibrosis progressing to liver cirrhosis is a consequence of chronic hepatitis C virus (HCV) infection. Antiviral therapy is aimed to eliminate HCV in order to prevent disease progression and late complications of cirrhosis. The aim of this study was to evaluate the long term effect of sustained virological response (SVR) on liver fibrosis. Methods: Liver stiffness (by FibroScan®) was examined in 67 sustained virologic responders to pegInterferon/ribavirin alone or in combination with a protease-inhibitor and in 29 nonresponders during follow-up (median: 6.0 years; range 1 – 15). All pa…
