Accelerated treatment strategy in inflammatory bowel diseases; is it associated with a change in the disease course?
Z Kürti, M Rutka, K Farkas, N Sipeki, P Golovics, B Lovász, Z Végh, K Gecse, L Kiss, I Altorjay, M Papp, T Molnár, P Lakatos · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
BACKGROUND AND AIMS: Evidence from new clinical trials in inflammatory bowel diseases (IBD) suggests that tight disease control and early aggressive therapy is associated with superior outcomes in patients with poor prognostic factors. The aim of the present study was to investigate the evolution of the treatment strategy and probability of resective surgery/colectomy in three IBD-centers according to the era of diagnosis. Methods: Data of 352 consecutive anti-TNF treated IBD patients (CD/UC: 296/56, males: 48.3%/42.9%, 1st anti TNF infliximab/adalimumab: 300/52, median age at diagnosis: 22/25.5 years, follow-up…
