Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy
C Rupp, K Friedrich, A Wannhoff, C Rauber, KH Weiss, W Stremmel, P Sauer, DN Gotthardt · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Bibliografische Angaben
Zusammenfassung
Background & Aims: Primary sclerosing cholangitis (PSC) is aggravated by dominant stenosis of the large bile ducts (DS) in the majority of cases. PSC patients with concomitant DS require endoscopic dilatation therapy to resolve biliary obstruction, but survival still remains impaired. We aimed to analyze the advantage of serum cholestatic markers to predict dilatation- and transplantation-free survival in PSC patients after endoscopic therapy. Methods: We analyzed 131 PSC patients that were treated at our tertiary care center with regard to serum cholestatic marker after endoscopic dilatation therapy. Clinical a…
