Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure
SH Stengel, C Engelmann, M Kiehntopf, PA Reuken, A Stallmach, T Berg, T Bruns · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Bibliografische Angaben
Zusammenfassung
Purpose/Objectives: Novel biomarkers capturing portal hypertension, macrophage activation, and systemic inflammation have been suggested as diagnostic tools to identify patients with spontaneous bacterial peritonitis (SBP). Since acute deterioration of liver function, portal hypertension and systemic inflammation are frequent consequences of bacterial infection, we compared the accuracy of a panel of proposed biomarkers for SBP controlling for the severity organ failure in a matched case-control design. Methods: Forty cases of SBP were identified from prospective registries and were matched to 80 cirrhotic contr…