CareLit Fachartikel
Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)
A Riedel, M Hornung, HJ Schlitt, EK Geissler, JM Werner · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Dokument
1145732
CareLit-ID
Jahr
2015
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Background: The immune system likely plays a significant role in the pathogenesis of fatty liver disease. The metabolic changes induce immunological responses resulting in nonalcoholic steatohepatitis (NASH) and further aggravation of the metabolic derangement in a feed-forward loop. However, most of the evidence regarding the immune system role in the context of NASH is based on the use of mouse models, which makes it difficult to rely on these conclusions for humans. Therefore, we aimed in this study to analyze the activation and function of several liver resident innate cell populations in a human in-vitro ce…
Schlagworte
After
Cytokine
Blood
Brefeldin A
Cytokines
Zeitschrift für Gastroenterologie
