CareLit Fachartikel

Priming with respiratory bacteria alters the airway epithelial response to subsequent viral infection

C Bellinghausen, F Gulraiz, EFM Wouters, G Rohde, FRM Stassen · Pneumologie · 2016 · Heft 02

Dokument
1145834
CareLit-ID
Jahr
2016
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
C Bellinghausen, F Gulraiz, EFM Wouters, G Rohde, FRM Stassen
Ausgabe
Heft 02 / 2016
Seiten
–
Erschienen: 2016-02-09 00:00:00
ISSN
0934-8387

Zusammenfassung

Background: The lungs of patients suffering from chronic respiratory diseases, such as chronic obstructive pulmonary disease, asthma or cystic fibrosis, are frequently colonized with potentially pathogenic bacteria. Additionally, these patients are particularly susceptible to viral infections, which can lead to acute exacerbation of the disease. In this study, we investigated if exposure to the most common respiratory bacterial pathogens alters the response of lung epithelial cells towards subsequent viral infection. Methods: We exposed bronchial epithelial cells (BEAS-2B and primary bronchial epithelial cells)…

Schlagworte

Bacteria Cytokines Cytokine Affect Asthma Lead Pneumologie