A prospective study to evaluate the efficacy of a standardized low calorie diet according to PNPLA3 genotype in patients with Non Alcoholic Fatty Liver Disease (NAFLD)
M Teufelhart, H Hofer, H Haslacher, R Winker, P Ferenci, B Mehl, C Rabitsch, M Trauner, T Scherzer · Zeitschrift für Gastroenterologie · 2016 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Approximately 30% of the Western population suffers from NAFLD, rising up to 90% in obese people. Complications of NAFLD include Non Alcoholic Steatohepatitis (NASH), liver cirrhosis, hepatocellular carcinoma as well as aggravation of diabetes and cardiovascular diseases. PNPLA3 is an important genetic factor associated with NAFLD. Aim of the study is to analyze the influence of PNPLA3 genotypes on the efficacy of a standardized low calorie liver diet (HEPAFAST, Bodymed, Kirkel, Germany). Methods: In this study 81 patients will be recruited and stratified according to PNPLA3 genotypes (27 patients pe…
