Potential therapeutic usefulness of the herbal preparation STW 5 in an experimental model of Crohn's disease

Einleitung: STW 5 is a multi-component herbal preparation consisting of standardized hydro-alcoholic extracts of bitter candytuft, lemon balm, chamomile, caraway fruit, peppermint leaf, Angelica root, milk thistle, celandine herb, and licorice root. It has been used successfully clinically in functional dyspepsia1 and irritable bowel syndrome2. We have reported earlier on its efficacy in experimental dextran sodium sulfate induced colitis as a model for ulcerative colitis3. Ziele: The present study was conducted to investigate underlying mechanisms involved in its use in 2,4,6-trinitrobenzene sulfonic acid (TNBS…