Pathologic complete response as independed prognostic factor after induction therapy followed by surgery in locally advanced non-small cell lung cancer

Introduction: Pathological complete response (pCR) after induction chemoradiation therapy (CRT) and followed by surgery in locally advanced non-small cell lung cancer (NSCLC) is associated with favorable long-term survival (LTS). The implication of pCR to daily clinical practice is yet poorly defined. The aim of the study was to identify the correlation of pCR and different prognostic factors influencing long-term survival (LTS), tumor recurrence pattern and progressive-free interval (PFI). Material and methods: A cohort patients with locally advanced stage III NSCLC treated with induction chemoradiation (CRT) a…