High-intensity focused ultrasound (HIFU) for tumor reduction and symptom relief in advanced pancreatic cancer

Purpose: Evaluation of ultrasound-guided high-intensity focused ultrasound (HIFU) in patients with inoperable pancreatic cancer to reduce tumor volume and tumor-associated pain. Material and methods: Fifteen patients with locally advanced inoperable pancreatic cancer and tumor-associated pain symptoms were treated by HIFU (n = 6 stage III, n = 9 Stage IV UICC). Thirteen patients underwent simultaneous standard chemotherapy. JC HIFU System (Chongqing, China HAIFU Company) was used with an ultrasound device for real-time imaging. Clinical evaluation was performed by imaging (US, CT, MRI) and validated standardized…