CareLit Fachartikel
Heme oxygenase-1 as intracellular positive acute phase protein in the rat liver: possible regulatory mechanisms
K Tron, R Novosyadlyy, B Haralanova-Ilieva, G Ramadori · Zeitschrift für Gastroenterologie · 2004 · Heft 02
Dokument
1161675
CareLit-ID
Jahr
2004
Publikation
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Metadaten
DOI
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Zusammenfassung
Background and Aims: Recently, it has been suggested that heme oxygenase-1 (HO-1) can be involved in acute phase response (APR). The purpose of the current work was to study the expression of HO-1 during localized inflammation in rats using in vivo and in vitro approaches. Methods: APR was induced by intramuscular injection of turpentine oil (TO). HO-1 and interleukin-6 (IL-6) mRNA expression in internal organs and injected muscle was evaluated by Northern blot hybridization. Expression at the protein level was analyzed by Western blot, immunohistochemistry (IHC) and ELISA. Alternatively, rat primary hepatocytes…
Schlagworte
Heme oxygenase-1
acute phase response
interleukin-6
liver
After
Acute-Phase Proteins
Work
Zeitschrift für Gastroenterologie
