Capsaicin receptor (CR), substance P (SP) and calcitonin gene-releated peptide (CGRP) in patients with large bowel diseases
A Dömötör, A Pár, G Pár, B Gasztonyi, A Király, Z Peidl, G Szekeres, J Szolcsányi, G Mózsik · Zeitschrift für Gastroenterologie · 2004 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: The capsaicin stimulates the capsaicin-sensitive nerves. I was proved that these fibers take place in the development of gastrointestinal mucosal damage/prevention (Mózsik, Abdel-Salam, Szolcsányi: Capsaicin-Sensitive Afferent Nerves in Gastric Mucosal Damage and Protection. Akadémia Kiadó, Bp. 1997). The development mechanisms of the human large bowel diseases widely studied, however their remained to be unknown. The aim of our study was to analyze the immundistribution of CR, CGRP and SP in different disorders of the human large bowel (inflammation, dysplasia only or together). Materials and methods: 55…