[18F]fluorodeoxyglucose (FDG) in vitro uptake in Hodgkin Lymphoma
U Banning, H Barthel, R Kluge, D Körholz, O Sabri · Klinische Pädiatrie · 2004 · Heft 05
Bibliografische Angaben
Zusammenfassung
Measurement of FDG uptake by PET is a highly sensitive method when it is used to monitor Hodgkin lymphoma treatment. However, interpretation of the follow-up FDG PET data is sometimes difficult, and there is still the need to reduce the number of false-positive/false-negative interpretations. To elucidate the circumstances influencing the quality of FDG PET in Hodgkin lymphoma, radiotracer uptake was studied in vitro in HDLM-2 cells. For that, the cells were treated with/without etoposide, and FDG uptake was measured at different time points. The obtained data were compared with %living cells as a parameter of c…