Enriched Environmental Housing Conditions and Hippocampal Structures of Aged Rats

Ageing comprises a number of physiological modifications, including structural changes. Hippocampal information processing can deteriorate during normal ageing in the absence of significant neuronal loss. These findings imply that a circuit-specific pattern of variability in the connectional organization of the hippocampus is coupled to individual differences in the cognitive outcome of normal ageing. We addressed the question how enriched environment influences hippocampal structures in aged rats. We used 19 hybrid Fischer 344* Brown Norway rats (FBNF1 rats) of following ages: 3 months (3 animals as controls),…