Transcranial DC Stimulation and Corticospinal Transmission

Transcranial DC stimulation (tDCS) is a non-invasive technique for the induction of long-lasting changes in neuronal excitability. tDCS of the human motor cortex leads to polarity-specific changes in corticospinal excitability: anodal tDCS facilitates TMS-evoked MEP while cathodal tDCS inhibits them. Here we report on an experiment on tDCS and corticospinal transmission in a patient with electrodes implanted in the high cervical epidural space for the relief of pain. TMS-evoked descending volleys and MEP from the right FDI were recorded before and after 5min of anodal tDCS of the left motor cortex. MEP amplitude…