Most effective stimulation site for severe intention tremor

Objective: To evaluate the optimal target for intention tremor in thalamic deep brain stimulation Background: DBS of the thalamic ventral intermedius nucleus (Vim-DBS) is an established therapy for patients with severe, otherwise intractable intention tremor. However, the optimal stimulation site for severe intention tremor is still a matter of debate. Methods: We studied 7 patients with ET and 6 patients with MS following implantation of stimulation electrodes for Vim-DBS. We analyzed the localization of the contacts of the quadripolar electrode (Medtronic, model 3387) on stereotactic x-ray images. Based on int…