Leucopenic renal transplant recipient effectively treated with recombinant human granulocyte colony-stimulating factor without increasing the incidence of rejection
H Podder, B Forgacs, V Pollard, Z Csapo, R Knight, B Kahan · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Leukopenia is a common adverse effect of immunosuppressive drugs, and increases the risk of infection in graft recipients. Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is widely used in leukopenic patients. However some data suggested that it increases the incidence of acute rejection in organ transplant patients. Objective: To evaluate the safety and efficacy of rhG-CSF in leukopenic renal transplant patients. Material and methods: From January 1. 2002- December 31. 2004 259 kidney transplantations were performed. The induction was either with Anti Thymocyte Globulin-thymoglobul…