The presence of HSPCO34 in colorectal cancer

Placental proteins are repressed after birth, but could be re- and overexpressed in various tumors. HSPCO34 is a protein abundantly expressed in placenta. The function of this protein is yet unknown and has higher expression also in liver, adrenal gland and some human neurogen tumors. Aims and methods: The aim of this pilot study was to investigate the presence of HSPCO34 in gastrointestinal tumors developed from neuroectoderma. All of the 10 patients had adenocarcinoma of the colon/sigma/rectum (median age: 68,5±9,5). Biopsy samples were taken from the tumor and the surrounding healthy tissue. After isolation o…