Detection of Helicobacter pylori's clarithromycin resistance by FISH. Possibilities and limitations

Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in humans. Estimates indicate that approximately 60% of the world population is colonized by this pathogen. Presence of H. pylori has been reported routineley in gastric biopsy samples since 1994 in our insitute. During this period, there was a decline in the number of H. pylori infected cases. One possible explanation might be a consistent detection and more efficient eradication of H pylori. International data reveal an increasing resistance to clarithromycin the central antibiotic used in treatment. The number of Hungaria…