EVALUATION OF EARLY LEFT VENTRICULAR DIASTOLIC DYSFUNCTION USING TISSUE DOPPLER ECHOCARDIOGRAPHY IN PATIENTS WITH TYPE 1 DIABETES MELLITUS

Purpose: Type 1 diabetes mellitus (DM 1) has been associated with left ventricular diastolic dysfunction even before the development of signs and symptoms of heart disease. The aim of this study was the early detection of diastolic dysfunction in asymptomatic patients with DM 1 by the use of tissue Doppler imaging (TDI) indices. Methods and Materials: We examined 23 patients (12 men, mean age 37.8±9.8 years) with DM 1 (Group A) and 20 normal controls (Group B) of comparable age and sex. All the participants underwent a standard 2-D and color Doppler echocardiographic study. Pulsed TDI was performed in apical 4-c…