Alteration of composition and diversity of the mucosa-associated fungal microflora in patients with inflammatory bowel disease
SJ Ott, M Musfeldt, K Smalla, T Kühbacher, J Hampe, KN Timmis, S Schreiber · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background and Aims: An altered bacterial diversity on the intestinal mucosa may reflect the net influence of life-style factors associated with the development of chronic inflammatory bowel diseases (IBD). While a reduced bacterial diversity as been reported in IBD, little is known about the fungal microflora, which is part of the fecal ecosystem. There is experimental and clinical evidence that fungi may be important trigger factors in the inflammatory pathophysiology. This study aimed at a systematic analysis of the intestinal fungal microflora in IBD. Patients and Methods: The mucosa-associated fungal microf…