Effect of baclofen therapy for duodenogastroesophageal reflux in a patient with distal subtotal gastrectomy with preservation of the lower esophageal sphincter and the vagal nerve

A 63-year-old male patient presented with a 2-year history of typical retrosternal heartburn solely during nightime, causing the patient to wake up between 3 and 4 o’clock in the morning. Magaldrate quickly relieved the symptoms, however the prophylactic use showed no benefit. The past medical history revealed distal subtotal gastrectomy with Roux-en-Y reconstruction for Stage 0 gastric cancer in the year 1997. A gastroscopy in June 2003 showed no esophagitis. He was started on several drugs, including PPIs, H2-antagonists, antacids and prokinetics, all with no benefit. In october 2004, the patient was sent to o…