Comparison of Thy–1 expression in human liver cirrhosis and different models of rat liver injury
T Mansuroglu, J Dudas, B Saile, D Batusic, G Ramadori · Zeitschrift für Gastroenterologie · 2006 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Thy–1 is a glycophosphatidylinositol-linked outer membrane leaflet glycoprotein. Until now the precise biological role of Thy–1 remains still obscure. One of the key characteristics of Thy–1 is that it´s expression often changes during cell differentiation. Changes in Thy–1 expression also accompany maturation and activation of several cell types, such as mesangial cells, mast cells, lung fibroblasts, thymocytes and astrocytes. In the current study we investigated Thy–1 expression in human liver cirrhosis and different models of rat liver injury. Methods: Thy–1 immunolocalization and mRNA expression was st…