CareLit Fachartikel
Aspergillus fumigatus conidia induce internalization dependent IFN-β and IP-10 expression in airway epithelial cells
C Hess, C Beisswenger, S Anders, K Schröppel, R Bals · Pneumologie · 2006 · Heft 02
Dokument
1163952
CareLit-ID
Jahr
2006
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Summary: Aspergillus fumigatus is a fungal pathogen of major clinical importance. Little is known about the role of human airway epithelial cells (HBEC) in host defense against A. fumigatus..It was the aim of the study to characterize the reaction of HBEC to the contact with conidiae from A. fumigatus. Methods: HBEC were infected with conidiae from A. fumigatus that were swollen for different time persiods. Total RNA from cells was isolated and reverse transcribed. IP-10, IFN-ß, IL-8 and hBD-2 expression on the mRNA level was determined by Real time RT-PCR. Cytokine levels in culture supernatants were determined…
Schlagworte
Aspergillus fumigatus
Aspergillus
Cytochalasin D
Cytokines
Cytokine
Pneumologie
