Central motor conduction examined with the triple stimulation technique correlates with pyramidal tract dysfunction and disability in patients with multiple sclerosis
U Hofstadt-van Oy, D Hagenburger, C Klawe, K Schröder · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Inflammatory lesions and axonal degeneration of central motor conduction pathways result in gait disturbance and contributes particularly to increasing disability in patients with multiple sclerosis. With conventional transcranial magnetic stimulation central conduction times can be estimated but axonal damage or conduction block of motor pathways is less sensitively detected to correlate well with disability. The triple stimulation technique (TST) examines the corticospinal tract by magnetic stimulation of cortical motor areas followed by sequenced distal and proximal peripheral nerve electric stimulation. The…