Randomised trial of organ- vs. pylorus-preserving pancreatic head resection

Introduction: In chronic pancreatitis, enlargement of the head of the pancreas develops in consequence of inflammatory alterations. In a prospective, randomized, control trial organ-preserving pancreatic head resection (OPPHR) was compared with pylorus-preserving pancreatoduodenectomy (PPPHR) to assess the advantages and disadvantages of each type of operation. Patients and Methods: Forty patients were allocated randomly to either the OPPHR (n=20) or the PPPHR (n=20) group. The interval between symptoms and surgery ranged from 5 to 12 years. The surgical data, postoperative complications, induction of diabetes m…