Identification of Helicobacter pylori and antrum erosion specific gene expression patterns in gastric biopsy samples by whole genomic microarray analysis
O Galamb, B Győrffy, F Sipos, D Szőke, S Spisák, A Németh, M Juhász, B Molnár, Z Tulassay · Zeitschrift für Gastroenterologie · 2006 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background: The high-density oligonucleotide microarray analysis gives an opportunity for studying the genetic and gene expression background of the diseases, even in small biopsy specimen. Aims: our aims were to identify Helicobacter pylori (HP) infection and antrum erosion associated gene expression patterns (GEP) and to compare the gene expression profile of HP+ and HP- gastric erosions to explain the possible role and effect of HP infection. Materials and Methods: Total RNA was extracted from frozen gastric biopsy specimens of 8 patients with HP+ antrum erosion and from 8 adjacent normal mucosa, from 8 patie…
