Pantoea agglomerans sepsis in a patient with chronic hepatitis C during peginterferon (PEG-IFN) plus ribavirin (RBV) therapy
T Korom, I Nagy, A Pálvölgyi, J Lonovics · Zeitschrift für Gastroenterologie · 2006 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background: Treatment with PEG-IFN is known to increase the risk of bacterial infections; nevertheless, severe sepsis is relatively uncommon. We report here a case of severe septic pyelonephritis complicating PEG-IFN plus RBV therapy in a pt with chronic hepatitis C. Case report: From April 2005, a 46-year-old woman with chronic hepatitis C (with a histological activity index of 6 and Scheuer's stage 2) was treated with PEG-IFN-alpha-2a in combination with RBV. By week 12, her treatment had yielded a good early virological response, and in the first 5 months there were no significant adverse events. At week 20,…