Small intestinal nodular lymphoid hyperplasia as the manifestation of common variable immunodeficiency in a patient with celiac disease

We report on the case of a 25 years old woman, with a history of hypogammaglobulinemia from the age of 14 years, who was admitted to a county hospital due to diarrhoea and edema of the lower extremities. By the results of the examinations performed, Crohn's disease was suggested as the possible cause of the symptoms. She was transferred to our Department for further investigations and treatment. Immunoelectrophoresis, the quantitative measurement of immunoglobulins, gastroscopy and colonoscopy (with respect to the terminal ileum) raised the possibility of nodular lymphoid hyperplasia as the manifestation of comm…