Clinicopathological and gene expression examination of young colorectal tumor patients

Introduction: In the colorectal tumorgenesis various genetic pathways are considered important in different age groups. In the view of prognosis, VEGF, GRP78 protein positivity among others seem to have overriding importance. Aims: We compared the gene expression profile of colorectal tumor patients under the age of 55 with data from previous studies. We also try to find the connection between the gene expression profile and the tumor invasion. Methods: In the period of 1995–2005 we had 152 colorectal tumor patients younger than 55 years. 71 of them were suitable for tissue array technique and statistical analys…