CareLit Fachartikel
Analysis of a single nucleotide polymorphism of icb–1 gene in women with breast cancer
A Springwald, O Treeck, R Görse, O Ortmann · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Dokument
1164752
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Icb–1 (C1orf38) is a human gene initially described by our group to be involved in in vitro differentiation processes of tumor cells derived from gynecological malignancies. Recently we reported various interactions between icb–1 and estrogen receptor-signaling. In this study we tested the hypothesis that polymorphisms in the icb–1 gene may be associated with increased risk for breast cancer. We investigated the icb–1 single nucleotide polymorphism (SNP) rs1467465 for association to breast cancer risk. A total of 634 women, made of 317 breast cancer cases and just as many controls, were included in the study. DN…
Schlagworte
breast cancer
single nucleotide polymorphism
Breast
Allele
Association
Affect
Blood
Tumor
Geburtshilfe und Frauenheilkunde
