Body mass index predicts alt normalization in patients treated for chronic hepatitis C
D Hueppe, E Zehnter, M Manns, G Teuber, T Dahhan, S Kaiser, U Meyer, T Witthöfft, R Mendel, B Möller, N Dikopoulos, J Brack, M Bilzer, G Tossing, S Mauss · Zeitschrift für Gastroenterologie · 2008 · Heft 09
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Zusammenfassung
Aims: A virological response to pegylated IFN and ribavirin is typically associated with a prompt decline in serum transaminases. The course of ALT normalization in treated patients with cHC has been observed within a German nationwide surveillance study and compared to achievement of HCV-RNA-negativity within the same cohort. Methods: Between 9/2003 and 02/2008, 284 active sites treated 3468 naïve and non-cirrhotic patients with a combination of PegIFN-alfa-2b and ribavirin. As the observational study is still ongoing, the subgroups of non-cirrhotic patients, who finished therapy (EOT) and the end of 6 months f…