Impact of Disseminated Tumor Cells in Bone Marrow and Circulating Tumor Cells in the Blood of Breast Cancer Patients
V Müller, T Fehm, W Janni, K Pantel · Geburtshilfe und Frauenheilkunde · 2009 · Heft 02
Bibliografische Angaben
Zusammenfassung
Keywords breast cancer, bone marrow, blood; disseminated tumor cells, circulating tumor cells Introduction The onset of subclinical tumor cell spread, as the putative precursor stage of subsequent solid metastases, can be assessed in breast patients with the detection of disseminated tumor cells (DTC) in bone marrow samples or circulating tumor cells in the blood (CTC) by immunocytochemical and molecular techniques. This is of clinical relevance especially in the context of a growing number of therapeutic options for the treatment of cancer patients. Progress in this field now enables clinical studies that shoul…