CareLit Fachartikel
Clinical testing of new molecular agents – do we have a clinical trial problem?
G von Minckwitz · Geburtshilfe und Frauenheilkunde · 2009 · Heft 02
Dokument
1165079
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
ja
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Bibliografische Angaben
Zusammenfassung
With the incremental knowledge on mechanisms of cancer development, a multitude of potential targets for new therapeutic agents have been discovered. Methodology for drug development has improved simultaneously, so that a tremendous amount of new compounds is waiting to be tested in pre-clinical and clinical studies for their potential efficacy against malignant diseases. New targeted agents can either inhibits selectively one target or can inhibit a range of targets of the same group or even different groups (so called „dirty drugs“). It is so far not clear which approach is more promising. High selectivity mig…
Schlagworte
Lead
Population
Blood
Treatment Failure
Drug Development
Blood Cells
Breast
Work
Geburtshilfe und Frauenheilkunde
