CareLit Fachartikel

Questioning the value of a possible non-invasive assessement of fibrogenic liver diseases as exemplified by serum based Fibrotest/Actitest

OA Gressner, N Beer, S Stanzel, AM Gressner · Zeitschrift für Gastroenterologie · 2009 · Heft 01

Dokument
1165170
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
OA Gressner, N Beer, S Stanzel, AM Gressner
Ausgabe
Heft 01 / 2009
Seiten
–
Erschienen: 2009-01-20 00:00:00
ISSN
0044-2771

Zusammenfassung

Introduction: Non-invasive, i.e. serum-based assessment of liver fibrosis is still an important challenge although multiple single and multiparametric panels of biomarkers have been proposed (1). Aim and Methods: (i) Haptoglobin, ALT, gammaGT, alpha 2-macroglobulin, apolipoprotein A1 and bilirubin in sera of 4 patients with histological proven fibrosis (F1-F4, A1-A3) were determined in 6 different quality-controlled laboratories. Inter-laboratory variations of the calculated Fibrotest Score for staging and Actitest Score for grading (both BioPredictiveTM), and their error ratios compared to the results obtained…

Schlagworte

Association Biomarkers Bilirubin Chemistry Biopsy Zeitschrift für Gastroenterologie