Multidrug- and extensively-drug resistant tuberculosis: a TBNET survey in Germany
B Eker, J Ortmann, G Migliori, G Sotgiu, R Mütterlein, R Centis, H Hoffmann, D Kirsten, T Schaberg, S Ruesch-Gerdes, C Lange · Pneumologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
We evaluated risk factors and treatment outcomes associated with multidrug-resistant (MDR)- and extensively drug-resistant (XDR)-tuberculosis (TB) in Germany in 2004–2006. In 184/4,557 (4%) of culture-positive TB cases, M. tuberculosis isolates were MDR. 148/184 (80%) patients with MDR-TB were born in countries of the former Soviet Union. 7/184 (4%) met XDR-TB criteria. In patients with XDR-TB hospitalization was longer (mean±SD 202±130 vs. 123±81 days; p=0.015) and resistance to all first line drugs was more frequent (36% vs. 86%; p=0.013) than in patients with MDR-TB. 74/184 (40%) patients received treatment w…
