STN-DBS modulates cortical control of urinary bladder in Parkinson's disease
J. Herzog, P.H. Weiss, A. Assmus, B. Wefer, C. Seif, H. Herzog, J. Volkmann, G. Deuschl, G.R. Fink · Aktuelle Neurologie · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Objective: To investigate the effect of subthalamic deep brain stimulation (STN-DBS) on cerebral bladder control measured by changes in regional cerebral blood flow (rCBF) during urodynamic bladder filling. Aims: STN-DBS has been shown to influence urinary bladder function in patients with Parkinson's disease (PD) by delaying first desire to void and increasing bladder capacity. Methods: In 11 PD patients (6 women) following bilateral STN-DBS, PET examinations and urodynamic measurements were performed in the medication OFF condition. The experimental design was factorial with the factors “stimulation“ (STN-DBS…