Diffusion tensor imaging of callosal motor fibres correlates with functional impairment in children with periventricular leukomalacia
I Koerte, B Kirmess, T Fuchs, S Berweck, W Flatz, A Danek, M Reiser, B Ertl-Wagner, F Heinen · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
Purpose: Diffusion tensor imaging (DTI) of transcallosal motor fibers is a potential paradigmatic parameter for hand motor function. We aimed to evaluate the microstructure (DTI), interhemispheric inhibitory competence as measured by transcranial magnetic stimulation (TMS) and hand motor function in children with mild cerebral palsy compared to normal controls. Methods: We examined 8 children (mean age 15.1±2.3) with known mild bilateral cerebral palsy and periventricular leukomalacia (PVL) and 12 healthy age-matched controls (mean age 15.3±2.7). Relative and fractional anisotropy (RA, FA) values were calculated…
