Symptomatic and neuropathic changes after endoscopic sphincterotomy (EST) in patients with sphincter of Oddi dysfuntion (SOD) and ERCP contrast filling pain (CFP)

Introduction: Recently, we proved a significant difference in the sensory current perception threshold (SCPT) ratio between the referred pain cutan area (RPA) and the contralateral area in patients with SOD. In a subgroup of patients with SOD, biliary pain could develop upon ERCP manipulation (tender papilla), or during intraductal contrast injection with ERCP (CFP). The aim of the present study was to prospectively analyse the symptomatic and neuropathic changes before and after EST in this subgroup of SOD patients having CFP. Methods: CFP evoked during ERCP in 7 patients out of 33 consecutive patients with pos…