Five years experience of pegylated interferon (PEG-IFN) plus Ribavirin (RBV) therapy in chronic hepatitis C

Introduction: PEG-IFN combined with RBV is currently regarded as the best antiviral treatment for chronic hepatitis C (CHC). Aim: To survey our experience with this treatment modality between 2004 and 2009. Patients and methods: The pts were treated for 12 months with once-weekly injections of PEG-IFN combined with 1.0–1.2g RBV daily. To date, 222 pts were enrolled in this course of therapy and the 6 months follow-up period. One hundred and fifty-five (70%) had not participated in previous IFN treatment (88 women, 67 men, age range (17–65 years, mean: 46.8 +/- 9.7), bodyweight 40–120kg (mean: 75.4 +/- 15.0). Six…