CareLit Fachartikel

Ga-68 DOTATOC-PET/CT in neuroendocrine tumors (NETs): Is an additional bone scan necessary for the detection of skeletal metastases?

S Strobel, W Bohle, TM Welzel, WG Zoller, T Eichele, H Bihl · Zeitschrift für Gastroenterologie · 2009 · Heft 06

Dokument
1166088
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
S Strobel, W Bohle, TM Welzel, WG Zoller, T Eichele, H Bihl
Ausgabe
Heft 06 / 2009
Seiten
–
Erschienen: 2009-06-18 00:00:00
ISSN
0044-2771

Zusammenfassung

Aim: In-111 DTPA-octrotide (In-111 DTPAOC) has proven its usefulness in the detection of somatostatin receptor (STTR) expressing NETs and their metastases. One of the major problems of this imaging modality is its limited sensitivity in detecting small lesions, particularly of the skeletal system, even if it is carried out in SPECT-technique. Ga-68 DOTA-D-Phe(1)-Tyr(3)-octreotide (Ga-68 DOTOATOC) is a new PET radiotracer with a higher affinity to STTR2 compared to In-111 DTPAOC. In this study we evaluated the clinical performance of Ga-68 DOTATOC-PET/CT and conventional bone scintigraphy in detecting skeletal me…

Schlagworte

Ga-68 Dotatoc-Pet Metastases Patients Scintigraphy Skeletal Detection Lesions Osseous In-111 Compared Conventional Zeitschrift für Gastroenterologie