On Chorea – quantitative and objective analysis – cross-sectional results of the TRACK-HD Study
S van den Bogaard, N Bechtel, A Sturrock, C Jauffret, M Say, JA Mills, TP Archarya, DR Langbehn, H Johnson, B Borowsky, A Durr, BR Leavitt, R Roos, SJ Tabrizi, B Landwehrmeyer, R Reilmann · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: Chorea is one of the most characteristic motor symptoms of Huntington's disease. One of the first descriptions dates back to the 19th century and was reported by George Huntington in his article “On chorea“. Chorea interferes with motor activities and has a significant impact on quality of life. Objective: To investigate if chorea can be assessed objectively and quantitatively, and if quantitative assessment can be related to disease stages as well as chorea subscores on the Unified Huntington's Disease Rating Scale Total Motor Score (UHDRS-TMS). Subjects and Methods: 123 controls, 120 pre-manifest g…
