Protein array reveals different protein levels in subcutaneous adipose tissue of patients with growth hormone deficiency in adulthood
D Gasperikova, J Ukropec, A Penesova, M Skopkova, M Vlcek, Z Radikova, V Belan, M Pura, J Payer, J Eckel, I Klimes · Diabetologie und Stoffwechsel · 2007 · Heft 07
Bibliografische Angaben
Zusammenfassung
The role of adipose tissue adipocytokines for development of the growth hormone deficiency (GHD)-related metabolic derangements has not yet been completely understood. Therefore, we screened the protein level of 120 adipokines in subcutaneous adipose tissue (ScAT) of patients with GHD in adulthood. Subjects and methods: Sixteen GHD (10M/6F) with BMI:27±1.0kg/m2, age 30±2yrs and sixteen controls matched for BMI, sex and age were included into the study. ScAT biopsies were performed after an overnight fast. Protein expression of adipokines was determined in tissue lysates using the RayBio®Human Cytokine Antibody A…
