Involvement of vascular endothelial growth factor and tumor necrosis factor-alpha in the process of neoangiogenesis in children with type 1 diabetes mellitus
K Zorena, J Myœliwska, M Myœliwiec, A Balcerska · Diabetologie und Stoffwechsel · 2007 · Heft 07
Bibliografische Angaben
Zusammenfassung
Backgrounds/Aims : Neoangiogenesis is a complex process, in which crucial role seems to be played by vascular endothelial growth factor (VEGF) and tumor necrosis factor (TNF-alpha). TNF-alpha may exhibit both stimulating and inhibiting effect on angiogenesis. Therefore it appeared to be worth of analysis to investigate the relation between TNF-alpha and VEGF and the clinical course of the disease in children with Diabetes Mellitus type 1 (DM1) Material and methods: 163 children aged 13.6±3.5 years diagnosed with DM1 from the Department of Paediatrics, Haematology, Oncology and Endocrinology at the Medical Univer…