Harmonics in frequency spectra: a contribution to differential diagnosis of tremor

Introduction: For quantification and differential diagnosis of tremor, electromyography (EMG) and accelerometry can be used supplementary to clinical assessment. Accelerometry essentially provides information regarding tremor amplitude and frequency. As there is a significant overlap in the frequencies of different tremor species, this parameter, however, is of limited value for specific diagnosis. EMG provides information about the patterns of agonistic and antagonistic muscle activity (alternating or co-contraction), but the specificity of this procedure is insufficient for individual diagnosis. For these reas…